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An anesthetic management of head and neck cancer reconstructive surgery in a patient having hemophilia A: a case report

Journal of Dental Anesthesia and Pain Medicine 2021³â 21±Ç 3È£ p.261 ~ 268
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À¯½ÂÈ­ ( Ryoo Seung-Hwa ) - Seoul National University School of Dentistry Department of Dental Anesthesiology
±ÇµµÇö ( Kwon Do-Hyun ) - Seoul National University School of Dentistry Department of Oral and Maxillofacial Surgery
ÀÌÁ¾È£ ( Lee Jong-Ho ) - Seoul National University School of Dentistry Department of Oral and Maxillofacial Surgery
¼­±¤¼® ( Seo Kwang-Suk ) - Seoul National University School of Dentistry Department of Dental Anesthesiology
±èÇöÁ¤ ( Kim Hyun-Jeong ) - Seoul National University School of Dentistry Department of Dental Anesthesiology
°¨¸íȯ ( Karm Myong-Hwan ) - Seoul National University School of Dentistry Department of Dental Anesthesiology

Abstract


Hemophilia A is a hemorrhagic disease caused by coagulation factor VIII deficiency. In head and neck cancer surgery, especially during a reconstructive one, complications can occur. These include hematomas due to bleeding which can then lead to flap ischemia, necrosis, and impaired wound healing. There are fewer cases of reconstructive surgery in patients with hemophilia A. Here in we report, a reconstructive surgery that involved mass resection, partial glossectomy (right), selective neck dissection (right, Levels I, II, III, IV), and reconstruction at the lateral arm free flap (left) in a 25-year-old man with hemophilia A. The surgery was successfully performed without any complications after pretreatment with Factor VIII concentrate, which has not been reported earlier.

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Factor VIII; Hemophilia A; Reconstructive Surgical Procedures; Squamous Cell Carcinoma of Head and Neck

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